HasAB BC
HasAB and HasBC¶
FASII enzyme
Protein, natural substrate, and chemistry¶
Available crystal structures¶
Table 1 - apo structures | pdb | year | resolution | notes | | --- | --- | --- | --- | | PH | PH | PH | PH |
Table 2 - co-crystal structures | pdb | year | resolution | ligand1 | ligand2 | notes | | --- | --- | --- | --- | --- | --- | | PH | PH | PH | PH | PH | PH |
Inhibitors¶
Table 3 - approved drugs with HasAB or HasBC activity | drug | year approved | clinical use | notes | | --- | --- | --- | --- | | PH | PH | PH | PH |
Table 4 - known inhibitor classes | scaffold/type | trial phase | notes | | --- | --- | --- | | PH | PH | PH |